Chemical Properties of Triamcinolone acetonide (CAS 76-25-5)

Triamcinolone acetonide

Download as PDF file Download as Excel file Download as 2D mole file Predict properties

InChI
InChI=1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3
InChI Key
YNDXUCZADRHECN-UHFFFAOYSA-N
Formula
C24H31FO6
SMILES
CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(C(=O)CO)O1
Molecular Weight1
434.50
CAS
76-25-5
Other Names
  • (11«beta»,16«alpha»)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
  • 9-Fluoro-11«beta»,16«alpha»,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone
  • 9-Fluoro-11«beta»,16«alpha»,17,21-tetrahydroxypregna-1,4-diene-3,20-dione-16,17-acetonide
  • 9-«alpha»-fluoro-11-«beta»,21-dihydroxy-16-«alpha»,17-«alpha»-isopropylidenedioxypregna-1,4-diene-3,20-dione
  • 9«alpha»-Fluoro-11«beta»,21-dihydroxy-16«alpha»,17-isopropylidenedioxy-1,4-pregnadiene,3,20-dione
  • 9«alpha»-Fluoro-16«alpha»-17«alpha»-isopropyledenedioxyprednisolone
  • 9«alpha»-Fluoro-16«alpha»-17«alpha»-isopropylidenedioxy-«DELTA»1-hydrocortisone
  • 9«alpha»-Fluoro-16«alpha»-hydroxyprednisolone 16«alpha»,17«alpha»-acetonide
  • Acetospan
  • Adcortyl
  • Adcortyl A
  • Aristocort
  • Aristocort A
  • Aristocort acetonide
  • Aristoderm
  • Aristogel
  • Azmacort
  • Coupe-A
  • Delphicort
  • Extracort
  • Flutone
  • Ftorocort
  • Kenacort-A
  • Kenalog
  • Kenalone
  • Ledercort cream
  • Nasacort
  • Nasacort AQ
  • Omcilon A
  • Panolog ointment
  • Polcortolon
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11«beta»,16«alpha»)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11«beta»,16«alpha»,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11«beta»,21-dihydroxy-16«alpha»,17-(isopropylidenedioxy)-
  • Pregna-1,4-diene-3,20-dione,9alpha-fluoro-11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxy-
  • Respicort
  • Rineton
  • Solodelf
  • TAC-3
  • TAC-40
  • Tramacin
  • Tri-Nasal
  • Triacet
  • Triaceton
  • Triam
  • Triam-Injekt
  • Triamcincolone acetonide
  • Triamcinolone 16,17-acetonide
  • Triamonide 40
  • Triamsinolone acetonide
  • Tricinolon
  • Trymex
  • Vetalog
  • Volon A
  • Volon A 40
  • Volonimat
Sources

Physical Properties

Property Value Unit Source
Δf -505.75 kJ/mol Joback Calculated Property
Δfgas -1121.41 kJ/mol Joback Calculated Property
Δfus 41.26 kJ/mol Joback Calculated Property
Δvap 116.25 kJ/mol Joback Calculated Property
logPoct/wat 2.42 Crippen Calculated Property
Pc 1768.38 kPa Joback Calculated Property
Tboil 1148.61 K Joback Calculated Property
Tc 1406.52 K Joback Calculated Property
Tfus 842.44 K Joback Calculated Property
Vc 1.19 m3/kg-mol Joback Calculated Property

Temperature Dependent Properties

Property Value Unit Temperature (K) Source
Cp,gas 1430.15 J/mol×K 1148.61 Joback Calculated Property
ΔfusH 45.29 kJ/mol 566.0 NIST
ΔfusH 45.29 kJ/mol 566.0 NIST

Molecular Descriptors

Joback and Reid Groups
-O- (ring) 2
-F 1
=CH- (ring) 3
-OH (alcohol) 2
=C< (ring) 1
-CH2- 1
-CH3 4
>C< (ring) 5
>C=O (nonring) 1
>CH- (ring) 4
-CH2- (ring) 4
>C=O (ring) 1

Similar Compounds

TRIAMCINOLONE DIACETATE. Betamethasone dipropionate. Budesonide. Triamcinolone. Prednisolone, 9alpha-fluoro-16alpha-methyl-, acetate. Betamethasone. Dexamethasone. 9Alpha-fluoro-16alpha-methylprednisolone-21-phosphate disodium salt. Pregn-4-ene-3,20-dione, 9alpha-fluoro-11,17alpha,21-trihydroxy-, 21- acetate. Dexamethasone, disodium phosphate. Triamcinolone tetra-TMS. Dexamethasone tetra-TMS. Betamethasone tetra-TMS. Isoflupredone, tetra-TMS. Nalmefene, bis(trifluoroacetate).

Find more compounds similar to Triamcinolone acetonide.

Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. The source is also providing more information like the publication year, authors and more. Take the time to validate and double check the source of the data.