Chemical Properties of Naloxone, bis(trimethylsilyl) ether

Naloxone, bis(trimethylsilyl) ether

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InChI
InChI=1S/C25H37NO4Si2/c1-8-14-26-15-13-24-21-17-9-10-19(29-31(2,3)4)22(21)28-23(24)18(27)11-12-25(24,20(26)16-17)30-32(5,6)7/h8-10,20,23H,1,11-16H2,2-7H3
InChI Key
TVMSEGLIEPBTNB-UHFFFAOYSA-N
Formula
C25H37NO4Si2
SMILES
C=CCN1CCC23c4c5c(O[Si](C)(C)C)ccc4CC1C2(O[Si](C)(C)C)CCC(=O)C3O5
Molecular Weight1
471.74
Sources

Physical Properties

Property Value Unit Source
logPoct/wat 4.67 Crippen Calculated Property

Similar Compounds

Oxymorphone, bis(trimethylsilyl) ether. Naloxone. Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5«alpha»)-. Codeinone, 14-hydroxy-. Naltrexone. Oxycodone. Oxymorphone. Nalbuphine, O,O,O-tris(trimethylsilyl) deriv.. Nalmefene, bis(trifluoroacetate). Nalmefene, trimethylsilyl ether. Nalorphine, bis(trimethylsilyl) ether. Thebaine. Hydromorphone, trimethylsilyl ether. Hydromorphone, tert-butyldimethylsilyl ether. Etorphine.

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