Chemical Properties of Hydrocortisone acetate

Hydrocortisone acetate

InChI
InChI=1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
InChI Key
ALEXXDVDDISNDU-MCHRFJOXSA-N
Formula
C23H32O6
SMILES
CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
Molecular Weight1
404.50
Other Names
  • 11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate, (11«beta»)-
  • 11«beta»,17«alpha»,21-Trihydroxypregn-4-ene-3,20-dione 21-acetate
  • 11«beta»,17«alpha»-Dihydroxy-21-acetoxypregesterone
  • 17-Hydroxycorticosterone acetate
  • 17-Hydroxycorticosterone-21-acetate
  • 17«alpha»-Hydrocorticosterone-21-acetate
  • 17«alpha»-Hydroxycorticosterone acetate
  • 21-Acetoxy-11«beta»,17-dihydroxypregn-4-en-3,20-dione
  • 21-Acetoxy-11«beta»,17-dihydroxypregn-4-ene-3,20-dione
  • 21-Acetoxy-11«beta»,17«alpha»-dihydroxypregn-4-ene-3,20-dione
  • Abbocort
  • Acetate-AS
  • Aceto-Cort
  • Anusol-HC
  • Bambicort
  • Berlison F
  • Biocortar
  • CaldeCort
  • Carmol HC
  • Chemysone
  • Colifoam
  • Collusul-HC
  • Colofoam
  • Compound F acetate
  • Cordes
  • Cortacream
  • Cortaid
  • Cortef acetate
  • Cortell
  • Cortes
  • Corticosterone, 17-hydroxy-, 21-acetate
  • Cortifoam
  • Cortisol acetate
  • Cortisol, 21-acetate
  • Cortril acetate
  • Cortril acetate-AS
  • Efcolin
  • Eye-Cort
  • Fernisone
  • HA
  • Hc45
  • Hycortole acetate
  • Hydrin-2
  • Hydrocal
  • Hydrocortisat
  • Hydrocortisone 21-acetate
  • Hydrocortistab
  • Hydrocortone acetate
  • Hydrosone
  • Hydroxycorticosterone acetate
  • Hysone-A
  • Isopto-Hydrocortisone
  • Lanacort
  • Lenirit
  • Mysone
  • NSC 741
  • Pabracort
  • Pregn-4-ene-3,20-dione, 11«beta»,17,21-trihydroxy-, 21-acetate
  • Pregn-4-ene-3,20-dione, 21-(acetoxy)-11,17-dihydroxy-, (11-«beta»)-
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11«beta»)-
  • Proctocort
  • Resicort
  • Sigmacort
  • Sintotrat
  • Velopural
  • Wycort
Cheméo is a service of Céondo GmbH, since 2007, we provide simulation, modelling and software development services for the industry. Do not hesitate to contact us for your projects.

Physical Properties

Property Value Unit Source
ΔfusH° 36.17 kJ/mol Joback Calculated Property
log10WS [-4.88; -4.30]   Show Hide
log10WS -4.30 Aq. Solubility Prediction
log10WS -4.88 Estimated Solubility
logPoct/wat 2.352 Crippen Calculated Property
McVol 309.510 ml/mol McGowan Calculated Property
Tfus 473.07 K Relay (1.0) Calculated Property

Cheméo can also estimate Normal Boiling Point Temperature, Critical Temperature, Critical Pressure, Critical Volume, Enthalpy of formation at standard conditions, Enthalpy of vaporization at standard conditions, Standard Gibbs free energy of formation, Acentric Factor, Ionization energy for this compound, but they fall outside the models' validated range, so they are not shown here. Open the prediction tool to compute them on demand.

Temperature Dependent Properties

Property Value Unit Temperature (K) Source
Cp,gas [1288.62; 1614.95] J/mol×K [1129.27; 1382.58] Show Hide
Cp,gas 1288.62 J/mol×K 1129.27 Joback Calculated Property
Cp,gas 1331.73 J/mol×K 1171.49 Joback Calculated Property
Cp,gas 1378.67 J/mol×K 1213.71 Joback Calculated Property
Cp,gas 1429.94 J/mol×K 1255.93 Joback Calculated Property
Cp,gas 1486.07 J/mol×K 1298.14 Joback Calculated Property
Cp,gas 1547.57 J/mol×K 1340.36 Joback Calculated Property
Cp,gas 1614.95 J/mol×K 1382.58 Joback Calculated Property
ΔfusH [36.95; 53.64] kJ/mol [480.00; 496.00] Show Hide
ΔfusH 53.64 kJ/mol 480.00 NIST
ΔfusH 36.95 kJ/mol 496.00 NIST

Similar Compounds

Pregn-4-ene-3,20-dione,11beta,17alpha,21-trihydroxy-,21 acetate. hydrocortisone tebutate. 11Beta,17alpha-dihydroxy-2beta,21-diacetoxypregn-4-ene-3,20-dione. 11Beta,17alpha-dihydroxy-2alpha,21-diacetoxypregna-4-ene-3,20-dione. Prednisolone Acetate. 11Beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione. Hydrocortisone. Hydrocortamate. prednisolone-21-trimethylacetate. 6Alpha,21-diacetoxy-11beta,17alpha-dihydroxypregn-4-ene-3,20-dione. 2Alpha,11beta,17alpha,21-tetrahydroxypregn-4-ene-3,20-dione. 6Alpha,11beta,17alpha,21-tetrahydroxypregn-4-ene-3,20-doine. Prednisolone. 4-Pregnene-3,11,20-trione, 17alpha,21-dihydroxy-, 21-acetate. Cortisone Acetate.

Find more compounds similar to Hydrocortisone acetate.

Sources

Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. The source is also providing more information like the publication year, authors and more. Take the time to validate and double check the source of the data.
These property values are available through the Cheméo API. A free account gives you an access key.