- InChI
- InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)
- InChI Key
- CMWTZPSULFXXJA-UHFFFAOYSA-N
- Formula
- C14H14O3
- SMILES
- COc1ccc2cc(C(C)C(=O)O)ccc2c1
- Molecular Weight1
- 230.26
- CAS
- 22204-53-1
- Other Names
-
- (+)-2-(6-Methoxy-2-naphthyl)propionic acid
- (+)-2-(Methoxy-2-naphthyl)-propionic acid
- (+)-2-(Methoxy-2-naphthyl)-propionsaeure
- (+)-6-Methoxy-«alpha»-methyl-2-naphthaleneacetic acid
- (+)-6-Methoxy-«alpha»-methyl-2-napthaleneacetic acid
- (+)-6-methoxy-.alpha.-methyl-2-naphthaleneacetic acid
- (+)-Naproxen
- (S)-(+)-naproxen
- (S)-2-(6-Methoxy-2-naphthyl)propionic acid
- (S)-6-Methoxy-«alpha»-methyl-2-naphthalene acetic acid
- (S)-6-methoxy-.alpha.-methyl-2-naphthaleneacetic acid
- (S)-Naproxen
- 2-(6-Methoxy-2-naphthyl)propanoic acid , (+)-
- 2-Naphthaleneacetic acid, 6-methoxy-«alpha»-methyl-, (+)-
- 2-Naphthaleneacetic acid, 6-methoxy-«alpha»-methyl-, (S)-
- 6-Methoxy-«alpha»-methyl-2-naphthaleneacetic acid (naproxen)
- Apo-Naproxen
- Bonyl
- CG 3117
- D-naproxen
- Diocodal
- Dysmenalgit
- Equiproxen
- Floginax
- Laraflex
- Laser
- MNPA
- Naixan
- Napren
- Naprium
- Naprius
- Naprosine
- Naprosyn
- Naprosyne
- Naprux
- Naxen
- Naxyn
- Nycopren
- Panoxen
- Prexan
- Propionic acid, 2-(6-methoxy-2-naphthyl)-, (+)-
- Proxen
- Proxine
- RS-3540
- Reuxen
- Veradol
- Xenar
- d-2-(6'-Methoxy-2'-naphthyl)-propionsaeure
- d-2-(6-Methoxy-2-naphthyl)propionic acid
- Cp,gas : Ideal gas heat capacity (J/mol×K).
- η : Dynamic viscosity (Pa×s).
- ΔfH°gas : Enthalpy of formation at standard conditions (kJ/mol).
- ΔfusH° : Enthalpy of fusion at standard conditions (kJ/mol).
- ΔfusH : Enthalpy of fusion at a given temperature (kJ/mol).
- ΔsubH : Enthalpy of sublimation at a given temperature (kJ/mol).
- ΔvapH° : Enthalpy of vaporization at standard conditions (kJ/mol).
- IE : Ionization energy (eV).
- log10WS : Log10 of Water solubility in mol/l.
- logPoct/wat : Octanol/Water partition coefficient.
- McVol : McGowan's characteristic volume (ml/mol).
- Inp : Non-polar retention indices.
- Tboil : Normal Boiling Point Temperature (K).
- Tfus : Normal melting (fusion) point (K).
- 1: Molecular weight from the IUPAC atomic weights tables.
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Physical Properties
Cheméo can also estimate Critical Temperature, Critical Pressure, Critical Volume, Standard Gibbs free energy of formation, Acentric Factor for this compound, but they fall outside the models' validated range, so they are not shown here. Open the prediction tool to compute them on demand.
Temperature Dependent Properties
| Property | Value | Unit | Temperature (K) | Source |
|---|---|---|---|---|
| ΔfusH | [29.41; 34.20] | kJ/mol | [428.50; 439.20] | 
|
| ΔfusH | 31.50 | kJ/mol | 428.50 | NIST |
| ΔfusH | 31.50 | kJ/mol | 428.50 | NIST |
| ΔfusH | 34.20 | kJ/mol | 428.80 | NIST |
| ΔfusH | 29.41 | kJ/mol | 439.20 | NIST |
| ΔsubH | 128.30 ± 0.50 | kJ/mol | 369.00 | NIST |
Correlations
| Property | Value | Unit | Temperature (K) | Source |
|---|---|---|---|---|
| Cp,gas | [238.03; 556.03] | J/mol×K | [273.00; 1000.00] |
Joback Predicted correlation
|
| Equation | Y = A + B·T + C·T² + D·T³ + E·T⁴ Y is Cp,gas in J/mol×K, T in K | |||
| Coefficient A | -1.81700e+01 | |||
| Coefficient B | 1.12574e+00 | |||
| Coefficient C | -7.36440e-04 | |||
| Coefficient D | 1.84900e-07 | |||
| Coefficient E | 0.00000e+00 | |||
| Temperature range, min. | 273.00 | |||
| Temperature range, max. | 1000.00 | |||
| Cp,gas | 238.03 | J/mol×K | 273.00 | Calculated Property |
| Cp,gas | 296.11 | J/mol×K | 353.78 | Calculated Property |
| Cp,gas | 347.13 | J/mol×K | 434.56 | Calculated Property |
| Cp,gas | 391.69 | J/mol×K | 515.33 | Calculated Property |
| Cp,gas | 430.37 | J/mol×K | 596.11 | Calculated Property |
| Cp,gas | 463.75 | J/mol×K | 676.89 | Calculated Property |
| Cp,gas | 492.43 | J/mol×K | 757.67 | Calculated Property |
| Cp,gas | 516.97 | J/mol×K | 838.44 | Calculated Property |
| Cp,gas | 537.98 | J/mol×K | 919.22 | Calculated Property |
| Cp,gas | 556.03 | J/mol×K | 1000.00 | Calculated Property |
| Property | Value | Unit | Temperature (K) | Source |
|---|---|---|---|---|
| η | [0.0016135; 0.0002400] | Pa×s | [428.54; 683.20] |
Joback Predicted correlation
|
| Equation | Y = exp(A + B/T + C·ln(T) + D·T^E) Y is η in Pa×s, T in K | |||
| Coefficient A | -1.15418e+01 | |||
| Coefficient B | 2.19087e+03 | |||
| Coefficient C | 0.00000e+00 | |||
| Coefficient D | 0.00000e+00 | |||
| Coefficient E | 0.00000e+00 | |||
| Comment | Liquid phase. Joback/Reid (1987), valid from Tf to 0.7·Tc. | |||
| Temperature range, min. | 428.54 | |||
| Temperature range, max. | 683.20 | |||
| η | 0.0016135 | Pa×s | 428.54 | Calculated Property |
| η | 0.0011755 | Pa×s | 456.84 | Calculated Property |
| η | 0.0008887 | Pa×s | 485.13 | Calculated Property |
| η | 0.0006929 | Pa×s | 513.43 | Calculated Property |
| η | 0.0005545 | Pa×s | 541.72 | Calculated Property |
| η | 0.0004536 | Pa×s | 570.02 | Calculated Property |
| η | 0.0003782 | Pa×s | 598.31 | Calculated Property |
| η | 0.0003206 | Pa×s | 626.61 | Calculated Property |
| η | 0.0002756 | Pa×s | 654.91 | Calculated Property |
| η | 0.0002400 | Pa×s | 683.20 | Calculated Property |
Similar Compounds
Find more compounds similar to Naproxen.
Mixtures
- Carbon dioxide + Naproxen + Acetone
- Propylene Glycol + Naproxen + Ethanol
- Naproxen + 1-Octanol
- Naproxen + Tetradecanoic acid, 1-methylethyl ester
- Trichloromethane + Naproxen
- Naproxen + Cyclohexane
- Naproxen + 1-Octanol + Water
- Naproxen + Tetradecanoic acid, 1-methylethyl ester + Water
- Trichloromethane + Naproxen + Water
- Naproxen + Ethanol + Ethyl Acetate
- Naproxen + Acetone + Water
- Carbon dioxide + Naproxen
- Naproxen + Acetone
- 2-Propanol + Naproxen
- Naproxen + Methyl Alcohol
- Naproxen + Ethanol
- Naproxen + Ethyl Acetate
- 1-Propanol + Naproxen
- n-Hexane + Naproxen
- Naproxen + Carbon Tetrachloride
Find more mixtures with Naproxen.
Sources
- Cheméo Relay (1.0)
- Cheméo Relay (1.0, beta) Beta: served but experimental, data-limited and below our cross-validation release bar; the Joback value is recommended where available.
- Crippen Method
- Solubility of naproxen in several organic solvents at different temperatures
- Thermodynamic study of the solubility of ibuprofen and naproxen in some ethanol + propylene glycol mixtures
- Solubility of naproxen in ethyl acetate + ethanol mixtures at several temperatures and correlation with the Jouyban-Acree model
- The determination and correlation of the solubility of naproxen in acetone and water mixtures
- High-pressure solubility of naproxen, nicotinamide and their mixture in acetone with supercritical CO2 as an anti-solvent
- Study of Glass Transition Phenomena in the Supercooled Liquid Phase of Methocarbamol, Acetaminophen and Mephensin
- Solubilities of Organic Semiconductors and Nonsteroidal Anti-inflammatory Drugs in Pure and Mixed Organic Solvents: Measurement and Modeling with Hansen Solubility Parameter
- Solubilities of the Drugs Benzocaine, Metronidazole Benzoate, and Naproxen in Supercritical Carbon Dioxide
- Solubility of Anti-Inflammatory, Anti-Cancer, and Anti-HIV Drugs in Supercritical Carbon Dioxide
- Solubility of (+)-(S)-2-(6-Methoxynaphthalen-2-yl) Propanoic Acid in Acetone, Methanol, Ethanol, Propan-2-ol, and Ethyl Ethanoate at Temperatures between (278 and 320) K
- Experimental and Theoretical Investigation of the Phase Behavior of Naproxen in Supercritical CO2
- Joback Method
- Aqueous Solubility Prediction Method
- McGowan Method
- NIST Webbook
Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. The source is also providing more information like the publication year, authors and more.
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