Chemical Properties of Fenofibrate

InChI

InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3

InChI Key

YMTINGFKWWXKFG-UHFFFAOYSA-N

Formula

C20H21ClO4

SMILES

CC(C)OC(=O)C(C)(C)Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1

Molecular Weight¹

360.84

Other Names

• 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester
• 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid, isopropyl ester (fenofibrate)
• Ankebin
• Antara
• Elasterin
• Fenobrate
• Fenogal
• Fenotard
• Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate
• Isopropyl 2-[p-(p-chlorobenzoyl)phenoxy]-2-methylpropionate
• Lipanthyl
• Lipantil
• Lipidex
• Lipidil
• Lipifen
• Lipirex
• Lipoclar
• Lipofene
• Liposit
• Lipsin
• NSC 281319
• Nolipax
• Procetofen
• Procetofene
• Procetoken
• Proctofene
• Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester
• Protolipan
• Secalip
• Sedufen
• Tricor

• C_p,gas : Ideal gas heat capacity (J/mol×K).
• η : Dynamic viscosity (Pa×s).
• Δ_fusH° : Enthalpy of fusion at standard conditions (kJ/mol).
• Δ_fusH : Enthalpy of fusion at a given temperature (kJ/mol).
• IE : Ionization energy (eV).
• log₁₀WS : Log10 of Water solubility in mol/l.
• logP_oct/wat : Octanol/Water partition coefficient.
• McVol : McGowan's characteristic volume (ml/mol).
• T_boil : Normal Boiling Point Temperature (K).
• T_fus : Normal melting (fusion) point (K).
• ¹: Molecular weight from the IUPAC atomic weights tables.

Physical Properties

Property	Value	Unit	Source
ΔfusH°	35.28	kJ/mol	Joback Calculated Property
IE	8.82	eV	Relay (1.0) Calculated Property
log10WS	-5.14		Relay (1.0) Calculated Property
logPoct/wat	4.680		Crippen Calculated Property
McVol	272.260	ml/mol	McGowan Calculated Property
Tboil	658.09	K	Relay (1.0) Calculated Property
Tfus	[352.05; 355.15]	K
Tfus	352.05	K	Thermodynamics of fenofibrate and solubility in pure organic solvents
Tfus	355.15	K	Phase equilibria of the binary systems of fenofibrate and dense gases (carbon dioxide, propane, trifluoromethane)
Tfus	354.75	K	Differential scanning calorimetry and thermally stimulated depolarization currents study on the molecular dynamics in amorphous fenofibrate
Tfus	353.62	K	Solubility of Fenofibrate in Different Binary Solvents: Experimental Data and Results of Thermodynamic Modeling

Cheméo can also estimate Critical Temperature, Critical Pressure, Critical Volume, Enthalpy of formation at standard conditions, Enthalpy of vaporization at standard conditions, Standard Gibbs free energy of formation, Acentric Factor for this compound, but they fall outside the models' validated range, so they are not shown here. Open the prediction tool to compute them on demand.

Temperature Dependent Properties

Property	Value	Unit	Temperature (K)	Source
Cp,gas	[800.37; 860.10]	J/mol×K	[888.79; 1126.50]
Cp,gas	800.37	J/mol×K	888.79	Joback Calculated Property
Cp,gas	813.56	J/mol×K	928.41	Joback Calculated Property
Cp,gas	825.36	J/mol×K	968.03	Joback Calculated Property
Cp,gas	835.84	J/mol×K	1007.64	Joback Calculated Property
Cp,gas	845.08	J/mol×K	1047.26	Joback Calculated Property
Cp,gas	853.14	J/mol×K	1086.88	Joback Calculated Property
Cp,gas	860.10	J/mol×K	1126.50	Joback Calculated Property
η	[0.0000307; 0.0004234]	Pa×s	[524.87; 888.79]
η	0.0004234	Pa×s	524.87	Joback Calculated Property
η	0.0002179	Pa×s	585.52	Joback Calculated Property
η	0.0001270	Pa×s	646.18	Joback Calculated Property
η	0.0000813	Pa×s	706.83	Joback Calculated Property
η	0.0000558	Pa×s	767.48	Joback Calculated Property
η	0.0000404	Pa×s	828.14	Joback Calculated Property
η	0.0000307	Pa×s	888.79	Joback Calculated Property
ΔfusH	32.40	kJ/mol	353.70	NIST

Similar Compounds

Find more compounds similar to Fenofibrate.

Mixtures

• Carbon dioxide + Fenofibrate
• Propane + Fenofibrate
• Methane, trifluoro- + Fenofibrate
• Methyl Alcohol + Fenofibrate
• Ethanol + Fenofibrate
• 1-Propanol + Fenofibrate
• 2-Propanol + Fenofibrate
• Ethyl Acetate + Fenofibrate
• Acetonitrile + Fenofibrate
• Acetone + Fenofibrate
• Ethanol + Water + Fenofibrate
• Acetone + Water + Fenofibrate

Sources

• Cheméo Relay (1.0)
• Cheméo Relay (1.0, beta) Beta: served but experimental, data-limited and below our cross-validation release bar; the Joback value is recommended where available.
• Crippen Method
• Crippen Method
• Thermodynamics of fenofibrate and solubility in pure organic solvents
• Phase equilibria of the binary systems of fenofibrate and dense gases (carbon dioxide, propane, trifluoromethane)
• Differential scanning calorimetry and thermally stimulated depolarization currents study on the molecular dynamics in amorphous fenofibrate
• Solubility of Fenofibrate in Different Binary Solvents: Experimental Data and Results of Thermodynamic Modeling
• Joback Method
• McGowan Method
• NIST Webbook

Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. The source is also providing more information like the publication year, authors and more. Take the time to validate and double check the source of the data.
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