Chemical Properties of Norethindrone (CAS 68-22-4)

Norethindrone

InChI
InChI=1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18,22H,4-11H2,2H3/t15?,16?,17?,18?,19?,20-/m0/s1
InChI Key
VIKNJXKGJWUCNN-BROHZWGRSA-N
Formula
C20H26O2
SMILES
C#C[C@]1(O)CCC2C3CCC4=CC(=O)CCC4C3CCC21C
Molecular Weight1
298.43
CAS
68-22-4
Other Names
  • (17-«alpha»)-17-Hydroxy-19-norpregn-4-en-20-yn-3-one
  • 17-Ethinyl-19-nor-testosterone
  • 17-Hydroxy-17-«alpha»-19-norpregn-4-en-20-yn-3-one
  • 17-Hydroxy-19-nor-17«alpha»-pregn-4-en-20-yn-3-one
  • 17-«alpha»-19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-
  • 17-«alpha»-Ethynyl-17-«beta»-hydroxy-4-estren-3-one
  • 17«alpha»-Ethinyl-17«beta»-hydroxy-«delta»(sup:4)-estren-3-one
  • 17«alpha»-Ethinyl-19-Nortestosterone
  • 17«alpha»-Ethinylestra-4-en-17«beta»-ol-3-one
  • 17«alpha»-Ethynyl-17-hydroxy-4-estren-3-one
  • 17«alpha»-Ethynyl-17-hydroxyest-4-en-3-one
  • 17«alpha»-Ethynyl-17«beta»-hydroxy-19-norandrost-4-en-3-one
  • 17«alpha»-Ethynyl-17«beta»-hydroxyestr-4-en-3-one
  • 17«alpha»-Ethynyl-19-nor-4-androsten-17«beta»-ol-3-one
  • 17«alpha»-Ethynyl-19-norandrost-4-en-17«beta»-ol-3-one
  • 17«alpha»-Ethynyl-19-nortestosterone
  • 17«alpha»-Ethynyl-3-oxo-4-estren-17«beta»-ol
  • 17«alpha»-Ethynyl-4-estren-17-ol-3-one
  • 17«beta»-Hydroxy-17«alpha»-ethynylestr-4-en-3-one
  • 17«beta»-Hydroxy-19-norpregn-4-en-20-yn-3-one
  • 19-Nor-17-ethinyltestosterone
  • 19-Nor-17«alpha»-ethynyltestosterone
  • 19-Nor-17«alpha»-pregn-4-en-20-yn-3-one, 17-hydroxy-
  • 19-Nor-ethindrone
  • 19-Norandrost-4-en-3-one, 17«alpha»-ethynyl-17«beta»-hydroxy-
  • 19-Norethinyltestosterone
  • 19-Norethisterone
  • 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (17«alpha»)-
  • 19-Nortestosterone, 17-ethynyl-
  • 19-nor-17«alpha»-Ethynyl-17«beta»-hydroxy-4-androsten-3-one
  • 19-nor-17«alpha»-Ethynylandrosten-17«beta»-ol-3-one
  • 4-Estren-17«alpha»-ethynyl-17«beta»-ol-3-one
  • Anhydrohydroxynorprogesterone
  • Anovule
  • Conludaf
  • Conludag
  • ENT
  • Estr-4-en-3-one, 17«alpha»-ethynyl-17-hydroxy-
  • Ethinyl-19-nortestosterone
  • Ethinylnortestosterone
  • Ethynylnortestosterone
  • Gestest
  • Menzol
  • Micronett
  • Micronor
  • Micronovum
  • Mini-Pe
  • Mini-pill
  • Minovlar
  • NET
  • NSC-9564
  • Nor-Q.D.
  • Nor-QD
  • Noralutin
  • Norcolut
  • Noresthisterone
  • Norethisteron
  • Norethisterone
  • Norethyndron
  • Norethynodrone
  • Norfor
  • Norgestin
  • Norluten
  • Norlutin
  • Norluton
  • Normapause
  • Norpregneninlone
  • Norpregneninolone
  • Primolut N
  • Proluteasi
  • SC 4640
  • Utovlan
  • Utovlar
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Physical Properties

Property Value Unit Source
ΔfusH° 26.55 kJ/mol Joback Calculated Property
log10WS -4.71 Aq. Solubility Prediction
logPoct/wat 3.493 Crippen Calculated Property
McVol 243.760 ml/mol McGowan Calculated Property
Inp [2625.00; 2625.00]   Show Hide
Inp 2625.00 NIST
Inp 2625.00 NIST
Tfus [476.65; 481.00] K Show Hide
Tfus 476.65 K Jean-Claude Bradley Open Melting Point Dataset (2014, CC0) Compiled value
Tfus 476.65 K Aq. Solubility Prediction
Tfus 479.00 ± 1.00 K NIST
Tfus 481.00 ± 1.00 K NIST

Cheméo can also estimate Normal Boiling Point Temperature, Critical Temperature, Critical Pressure, Critical Volume, Enthalpy of formation at standard conditions, Enthalpy of vaporization at standard conditions, Standard Gibbs free energy of formation, Acentric Factor, Ionization energy for this compound, but they fall outside the models' validated range, so they are not shown here. Open the prediction tool to compute them on demand.

Temperature Dependent Properties

Property Value Unit Temperature (K) Source
ΔfusH [39.60; 39.60] kJ/mol [479.00; 479.00] Show Hide
ΔfusH 39.60 kJ/mol 479.00 NIST
ΔfusH 39.60 kJ/mol 479.00 NIST
ΔfusS 82.70 J/mol×K 479.00 NIST

Correlations

Property Value Unit Temperature (K) Source
Cp,gas [311.97; 932.75] J/mol×K [273.00; 1000.00] Joback Predicted correlation Show Hide
EquationY = A + B·T + C·T² + D·T³ + E·T⁴
Y is Cp,gas in J/mol×K, T in K
Coefficient A-2.52390e+02
Coefficient B2.64652e+00
Coefficient C-2.36997e-03
Coefficient D9.08590e-07
Coefficient E0.00000e+00
Temperature range, min.273.00
Temperature range, max.1000.00
Cp,gas 311.97 J/mol×K 273.00 Calculated Property
Cp,gas 427.50 J/mol×K 353.78 Calculated Property
Cp,gas 524.69 J/mol×K 434.56 Calculated Property
Cp,gas 606.41 J/mol×K 515.33 Calculated Property
Cp,gas 675.53 J/mol×K 596.11 Calculated Property
Cp,gas 734.93 J/mol×K 676.89 Calculated Property
Cp,gas 787.47 J/mol×K 757.67 Calculated Property
Cp,gas 836.05 J/mol×K 838.44 Calculated Property
Cp,gas 883.51 J/mol×K 919.22 Calculated Property
Cp,gas 932.75 J/mol×K 1000.00 Calculated Property

Similar Compounds

Levonorgestrel. Ethisterone. Ethisterone. Linestrenol. Norethynodrel. Tibolone. Estr-4-en-3-one, 17«alpha»-hydroxy-17-methyl-. Norethandrolone. Norethisterone. Norethindrone Acetate. Calusterone. Bolasterone. 17-epi-Bolasterone. Nandrolone. Androsten-17-(beta)-ol-3-one, 17(alpha)-methyl-delta^4-.

Find more compounds similar to Norethindrone.

Sources

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Calculated This icon marks a calculated value or equation: a prediction, not a measurement.
Compiled This icon marks a compiled value or equation: taken from a data compilation such as ChemSep, not from an original measurement report.
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