Chemical Properties of Cyclizine

InChI

InChI=1S/C18H22N2/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18H,12-15H2,1H3

InChI Key

UVKZSORBKUEBAZ-UHFFFAOYSA-N

Formula

C18H22N2

SMILES

CN1CCN(C(c2ccccc2)c2ccccc2)CC1

Molecular Weight¹

266.39

Other Names

• (N-Benzhydryl)(N'-methyl)diethylenediamine
• 1-Diphenylmethyl-4-methylpiperazine
• 1-[di(phenyl)methyl]-4-methylpiperazine
• Bw 47-83
• Ciclizina
• Compound 47-83
• Marezine
• N-Benzhydryl-N'-methylpiperazine
• N-Benzhydryl-N-methyl piperazine
• N-Methyl-N'-benzhydrylpiperazine
• N-Methyl-N'-benzyhydrylpiperazine
• NSC 26608
• Nautazine
• Ne-devomit
• Neo-devomit
• Piperazine, 1-(diphenylmethyl)-4-methyl-
• Valoid
• Wellcome preparation 47-83
• Wellcome prepn. 47-83

• log₁₀WS : Log10 of Water solubility in mol/l.
• logP_oct/wat : Octanol/Water partition coefficient.
• McVol : McGowan's characteristic volume (ml/mol).
• I_np : Non-polar retention indices.
• T_fus : Normal melting (fusion) point (K).
• ¹: Molecular weight from the IUPAC atomic weights tables.

Physical Properties

Property	Value	Unit	Source
log10WS	-1.53		Aq. Solubility Prediction
logPoct/wat	3.023		Crippen Calculated Property
McVol	226.060	ml/mol	McGowan Calculated Property
Inp	[2010.00; 2035.00]
Inp	2020.00		NIST
Inp	2027.00		NIST
Inp	2027.00		NIST
Inp	2017.00		NIST
Inp	2010.00		NIST
Inp	2010.00		NIST
Inp	2020.00		NIST
Inp	2020.00		NIST
Inp	Outlier 2035.00		NIST
Inp	2020.00		NIST
Inp	2020.00		NIST
Inp	2010.00		NIST
Inp	2017.00		NIST
Tfus	378.65	K	Aq. Solubility Prediction

Cheméo can also estimate Normal Boiling Point Temperature, Critical Temperature, Critical Pressure, Critical Volume, Enthalpy of formation at standard conditions, Enthalpy of vaporization at standard conditions, Standard Gibbs free energy of formation, Acentric Factor, Ionization energy for this compound, but they fall outside the models' validated range, so they are not shown here. Open the prediction tool to compute them on demand.

Similar Compounds

Find more compounds similar to Cyclizine.

Sources

• Cheméo Relay (1.0, beta) Beta: served but experimental, data-limited and below our cross-validation release bar; the Joback value is recommended where available.
• Crippen Method
• Aqueous Solubility Prediction Method
• McGowan Method
• NIST Webbook

Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. The source is also providing more information like the publication year, authors and more. Take the time to validate and double check the source of the data.
Outlier This icon means that the value is more than 2 standard deviations away from the property mean.
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