Chemical Properties of Piroxicam (CAS 36322-90-4)

InChI

InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)

InChI Key

QYSPLQLAKJAUJT-UHFFFAOYSA-N

Formula

C15H13N3O4S

SMILES

CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O

Molecular Weight¹

331.35

CAS

36322-90-4

Other Names

• 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide
• 2H-1,2-benzothiazine-3-carboxyamide-4-hydroxy-2-methyl-N-2-pyridinyl-1,1-dioxide (piroxicam)
• 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid
• 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
• 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide1,1-dioxide
• 4-hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
• Artroxicam
• Baxo
• Bruxicam
• CHF 1251
• CP 16171
• Caliment
• Erazon
• Flogobene
• Geldene
• Improntal
• Larapam
• NSC 666076
• Pirkam
• Piroflex
• Reudene
• Riacen
• Roxiden
• Sasulen
• Solocalm
• Zunden
• dolonex
• feldene
• piroftal
• pyroxycam
• roxicam

• Δ_fusH : Enthalpy of fusion at a given temperature (kJ/mol).
• log₁₀WS : Log10 of Water solubility in mol/l.
• logP_oct/wat : Octanol/Water partition coefficient.
• McVol : McGowan's characteristic volume (ml/mol).
• I_np : Non-polar retention indices.
• ¹: Molecular weight from the IUPAC atomic weights tables.

Physical Properties

Property	Value	Unit	Source
log10WS	-4.16		Estimated Solubility
logPoct/wat	1.581		Crippen Calculated Property
McVol	225.000	ml/mol	McGowan Calculated Property
Inp	[1413.00; 1413.00]
Inp	1413.00		NIST
Inp	1413.00		NIST

Cheméo can also estimate Normal Boiling Point Temperature, Normal melting (fusion) point, Critical Temperature, Critical Pressure, Critical Volume, Enthalpy of formation at standard conditions, Enthalpy of vaporization at standard conditions, Standard Gibbs free energy of formation, Acentric Factor, Ionization energy for this compound, but they fall outside the models' validated range, so they are not shown here. Open the prediction tool to compute them on demand.

Temperature Dependent Properties

Property	Value	Unit	Temperature (K)	Source
ΔfusH	[34.50; 36.30]	kJ/mol	[473.00; 474.50]
ΔfusH	34.50	kJ/mol	473.00	NIST
ΔfusH	36.30	kJ/mol	473.40	NIST
ΔfusH	35.00	kJ/mol	473.90	NIST
ΔfusH	35.00	kJ/mol	474.50	NIST

Similar Compounds

Find more compounds similar to Piroxicam.

Mixtures

• D-Alanine + Piroxicam + Water
• D-Valine + Piroxicam + Water
• Piroxicam + Water
• Carbon dioxide + Piroxicam

Sources

• Cheméo Relay (1.0, beta) Beta: served but experimental, data-limited and below our cross-validation release bar; the Joback value is recommended where available.
• Crippen Method
• Measurement and modeling of mefenamic acid solubility in supercritical carbon dioxide
• Thermo-physical properties of l-Alanine/l-Valine in aqueous solutions of non steroid anti inflammatory drug dolonex at different temperatures: Volumetric and acoustic approach
• Solubility Measurement of Diclofenac Acid in the Supercritical CO2
• Estimated Solubility Method
• McGowan Method
• NIST Webbook

Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. The source is also providing more information like the publication year, authors and more. Take the time to validate and double check the source of the data.