Chemical Properties of Triamcinolone Acetonide (CAS 76-25-5)

Triamcinolone Acetonide

InChI
InChI=1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3
InChI Key
YNDXUCZADRHECN-UHFFFAOYSA-N
Formula
C24H31FO6
SMILES
CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(C(=O)CO)O1
Molecular Weight1
434.50
CAS
76-25-5
Other Names
  • (11«beta»,16«alpha»)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
  • 9-Fluoro-11«beta»,16«alpha»,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone
  • 9-Fluoro-11«beta»,16«alpha»,17,21-tetrahydroxypregna-1,4-diene-3,20-dione-16,17-acetonide
  • 9-«alpha»-fluoro-11-«beta»,21-dihydroxy-16-«alpha»,17-«alpha»-isopropylidenedioxypregna-1,4-diene-3,20-dione
  • 9«alpha»-Fluoro-11«beta»,21-dihydroxy-16«alpha»,17-isopropylidenedioxy-1,4-pregnadiene,3,20-dione
  • 9«alpha»-Fluoro-16«alpha»-17«alpha»-isopropyledenedioxyprednisolone
  • 9«alpha»-Fluoro-16«alpha»-17«alpha»-isopropylidenedioxy-«DELTA»1-hydrocortisone
  • 9«alpha»-Fluoro-16«alpha»-hydroxyprednisolone 16«alpha»,17«alpha»-acetonide
  • Acetospan
  • Adcortyl
  • Adcortyl A
  • Aristocort
  • Aristocort A
  • Aristocort acetonide
  • Aristoderm
  • Aristogel
  • Azmacort
  • Coupe-A
  • Delphicort
  • Extracort
  • Flutone
  • Ftorocort
  • Kenacort-A
  • Kenalog
  • Kenalone
  • Ledercort cream
  • Nasacort
  • Nasacort AQ
  • Omcilon A
  • Panolog ointment
  • Polcortolon
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11.beta.,16.alpha.)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11«beta»,16«alpha»)-
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11«beta»,16«alpha»,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11«beta»,21-dihydroxy-16«alpha»,17-(isopropylidenedioxy)-
  • Pregna-1,4-diene-3,20-dione,9alpha-fluoro-11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxy-
  • Respicort
  • Rineton
  • Solodelf
  • TAC-3
  • TAC-40
  • Tramacin
  • Tri-Nasal
  • Triacet
  • Triaceton
  • Triam
  • Triam-Injekt
  • Triamcincolone acetonide
  • Triamcinolone 16,17-acetonide
  • Triamonide 40
  • Triamsinolone acetonide
  • Tricinolon
  • Trymex
  • Vetalog
  • Volon A
  • Volon A 40
  • Volonimat
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Physical Properties

Property Value Unit Source
ΔfusH° 41.26 kJ/mol Joback Calculated Property
log10WS [-4.31; -3.89]   Show Hide
log10WS -3.89 Aq. Solubility Prediction
log10WS -4.31 Estimated Solubility
logPoct/wat 2.419 Crippen Calculated Property
McVol 314.510 ml/mol McGowan Calculated Property
Tfus 481.22 K Relay (1.0) Calculated Property

Cheméo can also estimate Normal Boiling Point Temperature, Critical Temperature, Critical Pressure, Critical Volume, Enthalpy of formation at standard conditions, Enthalpy of vaporization at standard conditions, Standard Gibbs free energy of formation, Acentric Factor, Ionization energy for this compound, but they fall outside the models' validated range, so they are not shown here. Open the prediction tool to compute them on demand.

Temperature Dependent Properties

Property Value Unit Temperature (K) Source
Cp,gas [1430.47; 2017.55] J/mol×K [1148.81; 1406.77] Show Hide
Cp,gas 1430.47 J/mol×K 1148.81 Joback Calculated Property
Cp,gas 1503.24 J/mol×K 1191.80 Joback Calculated Property
Cp,gas 1584.86 J/mol×K 1234.80 Joback Calculated Property
Cp,gas 1676.20 J/mol×K 1277.79 Joback Calculated Property
Cp,gas 1778.17 J/mol×K 1320.78 Joback Calculated Property
Cp,gas 1891.66 J/mol×K 1363.77 Joback Calculated Property
Cp,gas 2017.55 J/mol×K 1406.77 Joback Calculated Property
ΔfusH [45.29; 45.29] kJ/mol [566.00; 566.00] Show Hide
ΔfusH 45.29 kJ/mol 566.00 NIST
ΔfusH 45.29 kJ/mol 566.00 NIST

Similar Compounds

Triamcinolone diacetate. Nalmefene, bis(trifluoroacetate). azadirachtin. Betamethasone-17-valerate. Ethylmorphine. Nicocodine. Guanosine, N-trimethylsilyl-, 2',3',5'-tris(trimethylsilyl) ether. TCN. Crinan-11-ol, 1,2-didehydro-3-methoxy-, (3«beta»,5«alpha»,11R,13«beta»,19«alpha»)-. [2,2'-Bimorphinan]-3,3',6,6'-tetrol, 7,7',8,8'-tetradehydro-4,5:4',5'-diepoxy-17,17'-dimethyl-, (5«alpha»,6«alpha»)-(5'«alpha»,6'«alpha»)-. Vincamine. DIHYDROERGOKRYPTINE. Methyldesorphine. Ethylmorphine, trimethylsilyl ether. Ergocristine.

Find more compounds similar to Triamcinolone Acetonide.

Sources

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