Chemical Properties of Medroxyprogesterone Acetate

InChI

InChI=1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1

InChI Key

PSGAAPLEWMOORI-PEINSRQWSA-N

Formula

C24H34O4

SMILES

CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

Molecular Weight¹

386.53

Other Names

• (6«alpha»)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione
• (6«alpha»-Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-
• 17-Acetoxy-6«alpha»-methylprogesterone
• 17-Hydroxy-6-«alpha»-methylpregn-4-ene-3,20-dione acetate
• 17-Hydroxy-6«alpha»-methylpregn-4-en-3,20-dione acetate
• 17.alpha.-acetoxy-6.alpha.-methylprogesterone
• 17.alpha.-hydroxy-6.alpha.-methylprogesterone acetate
• 17«alpha»-Acetoxy-6-«alpha»-methylpregn-4-ene-3,20-dione
• 17«alpha»-Acetoxy-6«alpha»-Methylprogesterone
• 17«alpha»-Hydroxy-6«alpha»-methyl-4-pregnene-3,20-dione 17-acetate
• 17«alpha»-Hydroxy-6«alpha»-methylpregn-4-ene-3,20-dione acetate
• 17«alpha»-Hydroxy-6«alpha»-methylprogesterone acetate
• 6-Methyl-3,20-dioxopregn-4-en-17-yl acetate, (6«alpha»)-
• 6.alpha.-methyl-17.alpha.-hydroxyprogesterone acetate
• 6«alpha»-Methyl-17-acetoxyprogesterone
• 6«alpha»-Methyl-17R-hydroxyprogesterone acetate
• 6«alpha»-Methyl-17«alpha»-acetoxy-«DELTA»4-pregnene-3,20-dione
• 6«alpha»-Methyl-17«alpha»-acetoxypregn-4-ene-3,20-dione
• 6«alpha»-Methyl-17«alpha»-acetoxyprogesterone
• 6«alpha»-Methyl-17«alpha»-hydroxyprogesterone acetate
• 6«alpha»-Methyl-4-pregnene-3,20-dion-17«alpha»-ol acetate
• Amen
• Aragest
• Asconale
• Clinovir
• Colirest
• Curretab
• Cycrin
• DMPA
• DP150
• Depcorlutin
• Depo-Promone
• Depo-Provera
• Depo-Ralovera
• Depo-clinovir
• Depo-mpa
• Depomedroxyprogesterone acetate
• Deporone
• Depot-medroxyprogesterone acetate
• Farlutal
• Farlutin
• G-Farlutal
• Gestapuran
• Hematrol
• Hysron
• Lutopolar
• Lutoral
• MAP
• MPA
• Medroprogesterone acetate
• Medroxyacetate progesterone
• Medroxyprogesterone 17-acetate
• Metigestrona
• Metipregnone
• NSC-26386
• Nadigest
• Nidaxin
• Oragest
• Perlutex
• Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6«alpha»)-
• Pregn-4-ene-3,20-dione, 17-hydroxy-6«alpha»-methyl-, acetate
• Prodasone
• Progestalfa
• Progesterone, 17-hydroxy-6«alpha»-methyl-, acetate
• Progesterone, 17«alpha»-hydroxy-6«alpha»-methyl-, acetate
• Progeston
• Progevera
• Promone-E
• Provera
• Provera dosepak
• Proverone
• Ralovera
• Repromix
• Sirprogen
• Sodelut G
• Supprestral
• U 8839
• Veramix
• pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6.alpha.)-
• pregn-4-ene-3,20-dione, 17-hydroxy-6.alpha.-methyl-, acetate

• C_p,gas : Ideal gas heat capacity (J/mol×K).
• Δ_fusH° : Enthalpy of fusion at standard conditions (kJ/mol).
• log₁₀WS : Log10 of Water solubility in mol/l.
• logP_oct/wat : Octanol/Water partition coefficient.
• McVol : McGowan's characteristic volume (ml/mol).
• I_np : Non-polar retention indices.
• T_fus : Normal melting (fusion) point (K).
• ¹: Molecular weight from the IUPAC atomic weights tables.

Physical Properties

Cheméo can also estimate Normal Boiling Point Temperature, Critical Temperature, Critical Pressure, Critical Volume, Enthalpy of formation at standard conditions, Enthalpy of vaporization at standard conditions, Standard Gibbs free energy of formation, Acentric Factor, Ionization energy for this compound, but they fall outside the models' validated range, so they are not shown here. Open the prediction tool to compute them on demand.

Correlations

Property	Value	Unit	Temperature (K)	Source
Cp,gas	[411.10; 1189.24]	J/mol×K	[273.00; 1000.00]	Joback Predicted correlation
Equation			Y = A + B·T + C·T² + D·T³ + E·T⁴ Y is Cp,gas in J/mol×K, T in K
Coefficient A			-2.86380e+02
Coefficient B			3.26910e+00
Coefficient C			-2.92514e-03
Coefficient D			1.13166e-06
Coefficient E			0.00000e+00
Temperature range, min.			273.00
Temperature range, max.			1000.00
Cp,gas	411.10	J/mol×K	273.00	Calculated Property
Cp,gas	554.16	J/mol×K	353.78	Calculated Property
Cp,gas	674.71	J/mol×K	434.56	Calculated Property
Cp,gas	776.35	J/mol×K	515.33	Calculated Property
Cp,gas	862.64	J/mol×K	596.11	Calculated Property
Cp,gas	937.17	J/mol×K	676.89	Calculated Property
Cp,gas	1003.52	J/mol×K	757.67	Calculated Property
Cp,gas	1065.26	J/mol×K	838.44	Calculated Property
Cp,gas	1125.97	J/mol×K	919.22	Calculated Property
Cp,gas	1189.24	J/mol×K	1000.00	Calculated Property

Similar Compounds

Find more compounds similar to Medroxyprogesterone Acetate.

Mixtures

• Carbon dioxide + Medroxyprogesterone Acetate

Sources

• Cheméo Relay (1.0)
• Cheméo Relay (1.0, beta) Beta: served but experimental, data-limited and below our cross-validation release bar; the Joback value is recommended where available.
• Crippen Method
• Crippen Method
• Phase behavior of carbon dioxide + medroxyprogesterone acetate system at high pressures
• Joback Method
• McGowan Method
• NIST Webbook

Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. The source is also providing more information like the publication year, authors and more. Take the time to validate and double check the source of the data.
Calculated This icon marks a calculated value or equation: a prediction, not a measurement.
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