Chemical Properties of Thymidine

InChI

InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6?,7-,8-/m1/s1

InChI Key

IQFYYKKMVGJFEH-UHFFFAOYSA-N

Formula

C10H14N2O5

SMILES

Cc1cn(C2CC(O)C(CO)O2)c(=O)[nH]c1=O

Molecular Weight¹

242.23

Other Names

• 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 1-(2-Deoxy-«beta»-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
• 2'-Deoxythymidine
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-«beta»-D-erythro-pentofuranosyl)-5-methyl-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-«beta»-D-ribofuranosyl)-5-methyl-
• 5-Methyldeoxyuridine
• 5-Methyldeoxyurindine
• 5-methyl-2'-deoxyuridine
• DThyd
• Deoxythymidin
• Deoxythymidine
• Desoxy-thymidin
• NSC 21548
• Thymidin
• Thymidine, 2'-deoxy-
• Thymine-2-Desoxyriboside
• Thymine-2-deoxyriboside
• Thyminedeoxyriboside
• Uridine, 2'-deoxy-5-methyl-
• dT
• «beta»-D-Ribofuranoside, thymine-1 2-deoxy-

• PAff : Proton affinity (kJ/mol).
• BasG : Gas basicity (kJ/mol).
• C_p,solid : Solid phase heat capacity (J/mol×K).
• EA : Electron affinity (eV).
• logP_oct/wat : Octanol/Water partition coefficient.
• McVol : McGowan's characteristic volume (ml/mol).
• ρ_s : Solid Density (kg/m³).
• T_fus : Normal melting (fusion) point (K).
• ¹: Molecular weight from the IUPAC atomic weights tables.

Physical Properties

Property	Value	Unit	Source
PAff	[914.40; 948.30]	kJ/mol
PAff	948.30	kJ/mol	NIST
PAff	914.40	kJ/mol	NIST
BasG	915.90	kJ/mol	NIST
EA	0.40 ± 0.10	eV	NIST
logPoct/wat	-1.996		Crippen Calculated Property
McVol	166.450	ml/mol	McGowan Calculated Property
Tfus	460.15	K	Solubility of Anti-Inflammatory, Anti-Cancer, and Anti-HIV Drugs in Supercritical Carbon Dioxide

Cheméo can also estimate Normal Boiling Point Temperature, Critical Temperature, Critical Pressure, Critical Volume, Enthalpy of formation at standard conditions, Enthalpy of vaporization at standard conditions, Standard Gibbs free energy of formation, Acentric Factor, Ionization energy, Log10 of Water solubility in mol/l for this compound, but they fall outside the models' validated range, so they are not shown here. Open the prediction tool to compute them on demand.

Temperature Dependent Properties

Property	Value	Unit	Temperature (K)	Source
Cp,solid	[276.70; 306.65]	J/mol×K	[298.15; 368.15]
Cp,solid	276.70	J/mol×K	298.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	278.84	J/mol×K	303.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	280.97	J/mol×K	308.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	283.12	J/mol×K	313.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	285.25	J/mol×K	318.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	287.40	J/mol×K	323.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	289.53	J/mol×K	328.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	291.68	J/mol×K	333.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	293.81	J/mol×K	338.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	295.95	J/mol×K	343.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	298.09	J/mol×K	348.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	300.23	J/mol×K	353.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	302.37	J/mol×K	358.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	304.51	J/mol×K	363.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
Cp,solid	306.65	J/mol×K	368.15	Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
ρs	1460.00	kg/m3	298.15	Saturation molalities and standard molar enthalpies of solution of cytidine(cr), hypoxanthine(cr), thymidine(cr), thymine(cr), uridine(cr), and xanthine(cr) in H2O(l)

Similar Compounds

Find more compounds similar to Thymidine.

Mixtures

• Water + Thymidine
• Formamide, N,N-dimethyl- + Water + Thymidine
• Water + Thymidine + 2'-DEOXYGUANOSINE
• Carbon dioxide + Thymidine

Sources

• Cheméo Relay (1.0, beta) Beta: served but experimental, data-limited and below our cross-validation release bar; the Joback value is recommended where available.
• Crippen Method
• Crippen Method
• Saturation molalities and standard molar enthalpies of solution of cytidine(cr), hypoxanthine(cr), thymidine(cr), thymine(cr), uridine(cr), and xanthine(cr) in H2O(l)
• The partial molar heat capacity, expansion, isentropic, and isothermal compressions of thymidine in aqueous solution at T = 298.15 K
• Volumetric interaction coefficients for some nucleosides in aqueous solution at T= 298.15 K
• Volumetric studies on nucleic acid bases and nucleosides in aqueous guanidine hydrochloride solutions at T = (288.15 to 318.15) K and at atmospheric pressure
• Solvation behavior of some nucleic acid bases and nucleosides in water and in aqueous guanidine hydrochloride solutions: Viscometric, calorimetric and spectroscopic approach
• Homotactic enthalpic pairwise interactions of four deoxynucleosides (dU, dC, dG, dT) in dimethylformamide (DMF) + water mixtures at 298.15 K
• Solubility of Anti-Inflammatory, Anti-Cancer, and Anti-HIV Drugs in Supercritical Carbon Dioxide
• Molar Heat Capacities of Some Derivatives of Uridine and 2'-Deoxyuridine
• McGowan Method
• NIST Webbook

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